Iimveliso
Cytisine
Ulwazi olusisiseko lweCytisine
Ulwazi olusisiseko:
Ifomula yemichiza: C₁₁H₁₄N₂O
Ubunzima bemolekyuli: 190.24
Imbonakalo: Okungwevu-mhlophe ukuya kumthubi-mdaka ngekristale eqinileyo, okanye i-orthorhombic prismatic powder
Indawo yokunyibilikisa: 154-156℃
Ubuthi: Inetyhefu ethile kwaye kufuneka isetyenziswe ngononophelo
Ziziphi iziphumo ze-pharmacological ze-Cytisine?
● Umdla wokuphefumla: Umphumo wawo kwinkqubo yokuphefumla ufana ne-nicotine. Iyakwazi ukuhlaziya iziko lokuphefumula, ukuphucula ubunzulu kunye nokuphindaphinda ukuphefumla, kwaye umphumo wayo wokuphefumula unamandla kunomthamo ofanayo we phellodenine.
● I-Anti-arrhythmic: Inokunciphisa ukucaphuka kwe-myocardial kunye ne-conductivity, ukubetha kwentliziyo ecothayo, inqanda ukunyanzeliswa kwe-myocardial, kunye nokwandisa ixesha le-refractory. Ingasetyenziselwa ukuphatha i-tachycardia ye-ventricular kunye ne-palpitations esebenzayo
● Eminye imisebenzi: Uphononongo lwakutshanje lubonise ukuba inemisebenzi emininzi yezamayeza enjengokosuleleka ziintsholongwane, ukunqanda isilonda, ukwandisa iiseli ezimhlophe zegazi, kunye nokuchasana nomhlaza. Ngokubhekiselele kumsebenzi wokulwa nomhlaza, unokubangela ukuba i-apoptosis yeeseli zomhlaza kwaye isetyenziswe ngokubanzi ukuthintela ukwanda kweeseli ezahlukeneyo zethumba.
Ziziphi iimpembelelo ezithile zomlingo zeCytisine?
● Impembelelo yokuyeka ukutshaya: I-Plantarine yi-alkaloid ene-high binding affinity kwi-nicotine-acetylcholine receptor. Inokusebenza njenge-agonist yendawo ekhethiweyo, ukunciphisa ukuxhomekeka kwabatshayayo kwi-nicotine, ukunciphisa umnqweno wokutshaya, kunye nokunciphisa ubunzima beempawu zokuyeka i-nicotine.
● Impembelelo yokuphefumula yokuphefumula: Umphumo we-metronidine kwinkqubo yokuphefumula ufana ne-nicotine. Iyakwazi ukuvuselela iziko lokuphefumla, iphucula ubunzulu kunye namaxesha okuphefumla
● I-Anti-arrhythmic effect: I-Clindamine inokunciphisa ukucaphuka kwe-myocardial kunye ne-conductivity, ukubetha kwentliziyo ecothayo, inqanda ukunyanzeliswa kwe-myocardial contractility, kunye nokwandisa ixesha lokuchasa, ngaloo ndlela isetyenziselwa ukunyanga i-tachycardia ye-ventricular kunye nokusebenza kwe-palpitations.
● I-Anti-cancer effect: I-Plantarine inokubangela i-apoptosis yeeseli zomhlaza kwaye ithintele ukwanda kweeseli ezahlukeneyo ze-tumor ngokubhekiselele kumsebenzi wokulwa nomhlaza.
● Eminye imisebenzi: I-Clindamine nayo ineempembelelo zosulelo lwe-anti-microbial, anti-ulcer, ukwandisa iiseli ezimhlophe zegazi, ukuphucula ukusebenza kwengqondo kunye nokuchasana noxinzelelo.
Qhagamshelana:Judy Guo
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