Ixhaswe yiXi'an Rainbow Bio-Tech Co.,Ltd, uMqalisi wePhytochemical oKhokelayo
1. Intshayelelo ye-Isoquercetin
I-Isoquercetin (i-CAS No. 482-35-9), i-flavonol glycoside ephuma kwi-quercetin, i-polyphenolic compound yendalo efumaneka kwizityalo ezahlukeneyo, kuquka i-anyanisi, i-apula, i-buckwheat, kunye neyeza zonyango ezifana ne-Ginkgo biloba kunye ne-Hippophae rhamnoides. Njengesithako esiphambili se-bioactive, ifumene ingqwalasela ebalulekileyo kumachiza, i-nutraceutical, ukutya, kunye namashishini okuthambisa ngenxa yokuqina kwayo kwe-antioxidant, i-anti-inflammatory, kunye neyeza zonyango. Olu xwebhu lubonelela ngombono obanzi we-isoquercetin, kubandakanywa ubume bayo bekhemikhali, imigangatho yomgangatho, izicelo ezahlukeneyo, kunye nobuchule bobuchwepheshe be [Igama leNkampani Yakho] ekunikezeni izisombululo ze-premium isoquercetin.
2. Iimpawu ezisisiseko ze-Isoquercetin
2.1 Ulwakhiwo lweMichiza kunye neePropati
●Ifomula yeMolekyuli:C₂₁H₂₀O₁₁
● Ubunzima beMolekyuli:464.38 g/mol
● Ulwakhiwo lweMichiza:I-flavonol aglycone (quercetin) edityaniswe ne-molecule ye-glucose nge-bond glycosidic (3-O-glucoside).
● INkangeleko yoMzimba:Umgubo wekristale otyheli kunye nencasa ekrakra.
● Ukunyibilika:Inyibilika kancinci emanzini; Inyibilika kwi-ethanol, i-methanol, kunye ne-DMSO.
●Uzinzo:Ubuthathaka ekukhanyeni nakubushushu; uzinzile phantsi kweemeko zokugcina ezilawulwayo (2-8 ° C).
2.2 Imithombo yendalo
I-Isoquercetin ifumaneka kakhulu kwi:
●Izityalo:Buckwheat (Fagopyrum esculentum), itswele (Allium cepa), ii-apile (Malus domestica), kunye namaqunube (umzekelo, amaqunube, amaqunube).
● Amayeza amayeza:I-Ginkgo biloba (amagqabi), i-Hypericum perforatum (i-St. John's Wort), kunye ne-Sophora japonica (umthi we-pagoda waseJapan).
●Ukutya:Iti eluhlaza, iwayini ebomvu, kunye neentlobo ezithile zobusi.
2.3 I-Bioactivity kunye neendlela zokuSebenza
● Umsebenzi weAntioxidant:I-Scavenges i-radicals yamahhala (umzekelo, i-hydroxyl, i-superoxide) kwaye inqanda uxinzelelo lwe-oxidative ngokunyusa umqondiso we-Nrf2.
●Ukuthintela ukudumba:Icinezela i-cytokines ye-pro-inflammatory (TNF-α, IL-6) kwaye inqanda i-NF-κB indlela yokusebenza.
●Cardioprotective:Iphucula umsebenzi we-endothelial, inciphisa uxinzelelo lwegazi, kwaye inqanda ukuhlanganiswa kweplatelet.
● Umhlaza:Ibangela i-apoptosis kwiiseli zomhlaza (umzekelo, isifuba, imiphunga, i-colorectal) kwaye inqanda i-angiogenesis.
●Neuroprotective:Ikhusela kwizifo ze-neurodeergenerative (umzekelo, i-Alzheimer's, i-Parkinson) ngokunciphisa umonakalo we-oxidative kunye nokuvuvukala.
3. Umgangatho weMveliso: I-Premium-Grade Isoquercetin ngu-Xi'an Rainbow Bio-Tech CO.,Ltd
3.1 Ubunyulu kunye neMigangatho yoKwakha
●Ubunyulu:≥98% (i-HPLC assay, i-USP / EP / BP iyahambelana).
● Iintsimbi ezinzima:≤10 ppm (ICP-MS ivavanyiwe).
● Ukhuseleko lweMicrobiological:Ukuhambelana ne-USP <61> kunye <62> (inani leplate iyonke ≤1000 CFU / g, imvubelo / isikhunta ≤100 CFU / g, akukho E. coli okanye i-Salmonella).
● Iintsalela zeSolvent:≤0.5% (i-ethanol, i-methanol; i-GC-MS ihlolwe).
3.2 Inkqubo yeMveliso
I-Xi'an Rainbow Bio-Tech Co., Ltd isebenzisa ubunini, ukutsalwa kwe-eco-friendly kunye nenkqubo yokucoca:
1.Ukufumana izinto ezikrwada:Izicatshulwa zezityalo ze-premium-grade ezivela kwizinto zasendle.
2.Ukutsalwa:I-Ultrasound-assisted extraction (UAE) kunye ne-solvent-grade-grade solvents (i-ethanol / amanzi).
3.Ukucoca:Ikholomu ye-chromatography (i-silica gel / i-ODS) kunye ne-HPLC yokulungiselela ukuhlanjululwa okuphezulu.
4.Uqulunqo:Ukutshiza-ukomisa okanye umkhenkce-ukoma ukuvelisa umgubo ocolekileyo okanye iigranules ezinobungakanani obulungelelanisiweyo (10-100 μm).
3.3 Inkqubo yoLawulo loMgangatho (QC).
●Iilebhu zoBugcisa bobuGcisa:Ixhotyiswe ngeHPLC, LC-MS, NMR, kunye neGC-MS yovavanyo olungqongqo.
● Ukulandelelwa kweBatshi:Amaxwebhu apheleleyo ukusuka kwimathiriyeli ekrwada ukuya kwimveliso yokugqibela (ISO 22000:2018 iyahambelana).
● Iziqinisekiso:Izatifikethi zeKosher, Halal, kunye neFSSC22000.
4. Ukusetyenziswa kwe-Isoquercetin
4.1 Ishishini lezamayeza
● Uphuhliso lweziyobisi:
● Iiarhente zokulwa umhlaza:Iqulunqwe kunyango oludibeneyo (umzekelo, kunye ne-cisplatin) ukunyusa i-cytotoxicity kunye nokunciphisa iziphumo ebezingalindelekanga.
● Amachiza entliziyo:Isetyenziswe kwi-antihypertensive kunye ne-anticoagulant formulations (umzekelo, i-coenzyme Q10 + iipilisi ze-isoquercetin).
● Neuroprotective Drugs:Ifakwe kwiiprototypes zonyango lwe-Alzheimer (umzekelo, i-donepezil + isoquercetin capsules).
4.2 Izongezo zeNutraceutical neDietary
● IiNzuzo zempilo:
● Inkxaso yamajoni omzimba, ukulwa nokuguga, kunye nokulawulwa kwe-metabolic (umzekelo, ukulawula iswekile yegazi).
● Impilo yamalungu ( kunciphisa ukudumba kweosteoarthritis).
● Iimveliso zentengiso:
● Iipilisi (200-500 mg isoquercetin / ngosuku).
● Iziselo ezisebenzayo (umzekelo, iti eluhlaza efakwe kwi-isoquercetin).
4.3 Ishishini lokuTya neziselo
● Izithako ezisebenzayo:
● Isilondolozi sendalo (sandisa ubomi beshelufu ngomsebenzi we-antimicrobial).
● Ukuqiniswa kwesondlo (i-antioxidant etyetyiswe kwiijusi, i-snacks).
4.4 Izithambiso kunye noNonophelo lomntu
● Impilo yolusu:
● Ukukhuselwa kwe-Antioxidant kumonakalo we-UV.
● Ukuchasana nokuguga (ukukhuthazwa kwe-collagen synthesis, ukunciphisa imibimbi).
● Ukuthintela ukudumba kwesikhumba esibuthathaka (umzekelo, eczema, rosacea).
● Uqulunqo:
●IiSerum, iikhrimu, kunye nemaski (0.5-2% isoquercetin).
4.5 Unyango Lwezilwanyana
● Impilo Yezilwanyana:
● Ukuthintela ukudumba kwizilwanyana zasekhaya (umzekelo, i-osteoarthritis ezinjeni).
● Ukuxhaswa kwamajoni omzimba kwimfuyo (ukunciphisa umonakalo we-oxidative onxulumene noxinzelelo).
5. Xi'an Rainbow Bio-Tech Co.,Ltd – Iqabane lakho oliThembileyo kwiPhytochemical Innovation
5.1 Isishwankathelo seNkampani
Yasekwa ngo-2010, iXi'an Rainbow Bio-Tech Co., Ltd yinkokeli yehlabathi kuphando, uphuhliso, kunye nokuveliswa kwezinto eziphilayo ezisekelwe kwizityalo. Nge-20,000 m² indawo eqinisekisiweyo ye-GMP kunye neqela leenzululwazi ze-150+, sisebenza ngokukhethekileyo:
● Ukukhutshwa ngokwezifiso kunye nokucocwa kwe-flavonoids, i-alkaloids, kunye ne-polyphenols.
● Ukwenziwa kwekhontrakthi (CMO) kubathengi bamayeza kunye nezondlo.
● Imixube yobunini (umz., i-nanoecapsulated isoquercetin yokuphucula ukufumaneka kwezinto eziphilayo).
5.2 Izakhono zeR&D
● Ukusebenzisana:Intsebenziswano neeyunivesithi eziphambili (umzekelo, iYunivesithi yaseShaanxi Normal ) kunye namaziko ophando.
● Amalungelo awodwa abenzi:12+ amalungelo awodwa omenzi wechiza kwi-isoquercetin extraction, formulation, and applications.
5.3 UkuGqwesa kwiMveliso
●Umthamo:I-10 yeetoni ze-metric / unyaka we-isoquercetin (i-95-99% ubumsulwa).
●Uzinzo:Akukho mveliso yenkunkuma ngokuphinda kusetyenziswe isinyibilikisi esivaliweyo.
● Ukufikelelwa kweHlabathi:Kunikezelwe abathengi abangama-200+ kumazwe angama-30+ (umzekelo, eU.SA, EU, Japan, Australia).
5.4 Iinkonzo zoMthengi-ziphakathi
● Inkxaso yobuGcisa:Ukulungiselela idosi elungiselelwe wena (umzekelo, iDMF, CEP).
●Ukuthotyelwa koMmiselo:Inkxaso epheleleyo ye-FDA, i-EFSA, kunye nokufakwa kwe-TGA.
●Ukhetho lokuPakisha:Ukupakishwa ngokwezifiso (iingxowa ze-aluminium foil, iidramu ze-HDPE) kunye nokukhuselwa komswakama / ukukhanya.
6. Isiphelo: Isoquercetin - Isisombululo seNdalo kwiMingeni yanamhlanje
I-Isoquercetin's bioactivity eguquguqukayo iyibeka njengesithako sembombo kukhathalelo lwempilo, isondlo, kunye nokhathalelo lomntu. I-Xi'an Rainbow Bio-Tech Co., Ltd ukuzibophelela kumgangatho, ukuveliswa kwezinto ezintsha, kunye nokuzinza kuqinisekisa ukuba iimveliso zethu ze-isoquercetin zihlangabezana neyona migangatho iphezulu yehlabathi. Nokuba ikuphuhliso lwamachiza, izongezo zokutya, okanye imixube yezithambiso, izisombululo zethu zixhobisa imizi-mveliso ukusebenzisa amandla endalo kubomi obunempilo.
Joyina izandla ne-Xi'an Rainbow Bio-Tech Co.,Ltd – apho inzululwazi idibana nendalo.
Ixesha lokuposa: Apr-01-2025